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Contents

Introduction

1 History

A Short History of the Diagnosis and Treatment of Cerebral AVMs

Pre-17th Century

17th–19th Century

Treatment of Extracranial AVM in Earlier and Present Time

Intracranial Angiomas

The Contributions of Virchow and his Contemporaries

Early Clinical Observations on Intracranial AVMs

Surgical Treatment of Cerebral AVMs (1889–1930)

Neurosurgical Approaches Prior to the Introduction of Angiography (1928)

Neurosurgical Treatment of Intracranial AVM Following the Introduction of Angiography (1930)

The Limitations of Surgery

Conservative versus Surgical Treatment

Summary and Outlook

Diagnosis

Surgery

2 Embryology

Miguel Marin-Padilla

A. Embryogenesis of the Early Vascularization of the Central Nervous System

Introduction

Perineural Vascular Territory of the CNS Vasculature

Interneural Vascular Territory of the CNS Vasculature

Composition and Organization of the Pial Vascular Plexus

Vascular Perforation of the CNS Surface by Pial Vessels

Vascular Approach and Contact with the CNS Surface

Endothelial Filopodia Perforation of CNS Surface

In Situ Formation of New Intraneural Vessels

Establishment of the VRC and Interneural Vascular Territory

Intraneural Vascular Territory of the CNS Vasculature

Conclusions

B. Vascular Malformation of the Central Nervous System. Embryological Considerations

Capillary Telangiectasias and Cavernous Angiomas

Venous and Arteriovenous Malformations

Sturge-Weber-Dimitri’s Disease

3 Pathological Considerations

Pathogenesis

Classification of Vascular Malformations

Nomenclature

Classification

The Author’s Classification

Location of AVMs

Localization

Localization of the AVM Within the Brain

I. Surface Lesions (visible on exploration on the surface of the brain)

II. Deep Lesions (invisible at exploration on the surface)

The Nidus

The Concept of Compartments

Compact and Diffuse Lesions

Sizes, Shapes, and Elements of AVMs

Sizes of AVM

Shape

Pure Fistulous AVM

Elements of an AVM

Arterial Feeders

Venous Drainage

Sinuses

Enlargement, Growth, and Regrowth of AVMs

Enlargement

Growth

Pseudo-Growth

True Growth of the AVM

Spontaneous Thrombosis and Regression of AVMs

Multiple AVMs

Multiple Cerebral AVMs

Intracranial and Intraspinal AVMs

Association of Persistent Trigeminal Artery and AVM

Association of Aneurysm and AVM

Intracranial AVM with Stenosis and Occlusion of Major Vessels

Arterial

Moya-Moya Disease

Venous

AVM Associated with Other Pathological Entities

Tumors

4 Hemodynamics

Introduction

Hemodynamics

The Physics of Fluids and Blood Flow

Pressure, Flow, and Resistance

The Nature of Blood

Laminar versus Turbulent Flow

Tortuosity of Vessels

Vascular Distensibility

Cerebral Circulation: Functional Anatomy of the Cerebral Circulation

Neuronal Innervation

Microcirculation

AVM Structure

Enlargement of AVMs

Autoregulation

Normal Perfusion Pressure Breakthrough

Comments on the Normal Perfusion Pressure Breakthrough Theory

Effects of AVMs upon Cerebral Function

Local Mass Effect

Obstruction

Hemorrhage

Vascular Steal

Systemic Effects

Operative Considerations with Regard to Hemodynamics

Preoperative Evaluation

Operative Techniques

Postoperative Care

5 Diagnosis and Follow-up of Patients with Cerebral AVM using Doppler Ultrasound

Herbert M. Keller

6 Neuroradiological Evaluation

A. Valavanis

Computed Tomography

Magnetic Resonance Imaging (MRI)

Cerebral Angiography

Technique

Erroneous Findings

Angiographic Classification

Angiographic Investigation

Limitations of Conventional Selective Angiography

Venous Phase

Associated Aneurysms

Spasm

Summary

7 Microsurgical Anatomy of the Brain

Supratentorial Sulci and Fissures

Fissures

Interhemispheric (Longitudinal) Fissure

Sylvian Fissure

Transverse Fissure

Vascular Patterns Relating to Supratentorial Sulci

Infratentorial Sulci and Fissures

Organization of the Cerebral Microcirculation

The Venous System of the Brain

The Veins of Posterior Fossa

The Collateral Circulation

I Extracranial Arterial Circle

II Dural Arterial Circle

III Basal Cerebral Arterial Circle of Willis

IV Cortical Interhemispherical and Intrahemispherical Arterial Circle

V Cerebellar Arterial Circle

VI Transcranial Arterial Circle

VII Spinal Arterial Circle

VIII Vertebrocervical Arterial Circle

IX Primitive Arterial Circle

Pathology of Collateral System

8 Cortical Blood Vessels of the Human Brain

H. M. Duvernoy

Blood Vessels of the Cerebral Cortex

I Pial Vessels

The Pial Arterial Network

The Pial Venous Network

Pial Vessels: Discussion

Intracortical Vessels

Blood Vessels of the Cerebellar Cortex

I Pial Vessels

II Intracortical Vessels

9 Anatomy of the Calcarine Sulcus

S. Kubik and B. Szarvas

Development

Nomenclature of the Various Parts of the Calcarine Sulcus

The Location of the Meeting Point

Anatomical Variations of the Pars Posterior

Variations in the Terminal Part of the Pars Posterior

Side-Branches and Connections

Pars Anterior of the Calcarine Sulcus

Variations in Course

Connections and Side-Branches

Inner Structure of the Sulcus Calcarinus

Measurements

The Relationship Between the Sulcus Calcarinus and the Calcar Avis, Posterior Horn and Optic Radiation

References

Index

Microneurosurgery, Volume IIIA

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