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Excessive Hemolysis

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Anemia due to destruction of RBC is much less common and rarely associated with blood loss or bone marrow failure. These anemias are caused by defects that are either extrinsic or intrinsic to the RBC. For example, an anemia with extrinsic defects is autoimmune hemolysis. An anemia with intrinsic defects is sickle cell disease.

Laboratory Assessment of Nutritional Status: Bridging Theory & Practice

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