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3.2.3 If Amoxicillin Is To Be Prescribed 3.2.3.1 Amoxicillin Oral Suspension

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Calculate the dose of amoxicillin suspension in mL for a 10‐year‐old child weighing 32 kg (70 lbs) (Table 3.6).

 Dose required: 25–45 mg/kg/day divided bid or 20–40 mg/kg/day q8h (this is given by the manufacturer).Table 3.5 How to calculate dose if the child can swallow tabletsStep 1 Convert pounds to kg:70 lb × 1 kg/2.2 lb = 31.8 kgStep 2 Calculate the dose in mg:31.8 kg × 15 mg/kg/day = 477 mg/dayStep 3 Divide the dose by the frequency:477 mg/day ÷ 3 (tid) = 159 mg/dose q8hThe total dose is 159 mg every 8 hours. Since the tablets only come in 250 and 500 mg, it is probably best to prescribe the oral suspension to be more precise.Table 3.6 Calculating the dose of amoxicillin suspension in mL for a 10‐year‐old child weighing 70 lbStep 1 Convert pounds to kg:70 lb × 1 kg/2.2 lb = 31.8 kgStep 2 Calculate the dose in mg:31.8 kg × 40 mg/kg/day = 1272 mg/dayStep 3 Divide the dose by the frequency:1272 mg/day ÷ 3 (tid) = 424 mg/dose bidStep 4 Convert the mg dose to mL:424 mg/dose ÷ 125 mg/5 mL = 3.39 mL bidStep 5 Convert mL into teaspoonfulsa3.39 mL ÷ 5 mL = 0.68 teaspoonful Rx: amoxicillin oral suspension 125 mg/5 mLDisp: 100 mL bottleSig: Take 3.4 cc orally three times a day for 7 days for dental infectionNote: mL (milliliters) is sometimes referred to as cc or cubic centimeters. Usually, a medical dropper will have markers in cc which is the same as mL. There is probably less misinterpretation when mL is used rather than cc.a Each teaspoonful is 5 mL.

 How supplied: suspension comes in concentrations of 125 mg/5 mL, 250 mg/5 mL, 250 mg/mL, 400 mg/mL (100 mL bottle).

Advise the parent to get a medicine dropper/spoon rather than using an ordinary teaspoon because of variations in measurements of a teaspoonful. After amoxicillin solution is mixed, it is best to store it in a refrigerator between 2 °C and 8 °C (36–46 °F); do not freeze. Throw away any unused medicine after 14 days.

The Dentist's Drug and Prescription Guide

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