| Chapter I | A Great Transaction in Land |
| Chapter II | Beginning a Long Journey |
| Chapter III | From the Lower to the Upper River |
| Chapter IV | Novel Experiences among the Indians |
| Chapter V | From the Tetons to the Mandans |
| Chapter VI | Winter among the Mandans |
| Chapter VII | From Fort Mandan to the Yellowstone |
| Chapter VIII | In the Haunts of Grizzlies and Buffalo |
| Chapter IX | In the Solitudes of the Upper Missouri |
| Chapter X | To the Great Falls of the Missouri |
| Chapter XI | A the Heart of the Continent |
| Chapter XII | At the Sources of the Missouri |
| Chapter XIII | From the Minnetarees to the Shoshonees |
| Chapter XIV | Across the Great Divide |
| Chapter XV | Down the Pacific Slope |
| Chapter XVI | Down the Columbia to Tidewater |
| Chapter XVII | From Tidewater to the Sea |
| Chapter XVIII | Camping by the Pacific |
| Chapter XIX | With Faces turned Homeward |
| Chapter XX | The Last Stage of the Columbia |
| Chapter XXI | Overland east of the Columbia |
| Chapter XXII | Camping with the Nez Perces |
| Chapter XXIII | Crossing the Bitter Root Mountains |
| Chapter XXIV | The Expedition Subdivided |
| Chapter XXV | Adventures on the Yellowstone |
| Chapter XXVI | The End of a Long Journey |
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