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Why Does the Thyroid Become Underactive?

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There are two main types of hypothyroidism: primary, when the thyroid is the source of problems; and secondary, when a fault in the hypothalamus or pituitary has a knock-on effect on the thyroid.

Primary hypothyroidism can be brought on by:

• thyroiditis (inflammation of the thyroid), a feature of Hashimoto’s thyroiditis (see page 49) and postpartum thyroiditis (PPT)

• surgical or medical treatment for an overactive thyroid (see Chapter 5) or surgery and/or radiotherapy for certain kinds of cancer

• prescription medications and over-the-counter drugs containing iodine (iodides), such as lithium for treating manic-depression, and some cough remedies

• congenital (inborn) problems affecting the thyroid, such as absence or abnormal development of the thyroid or errors of metabolism (see Chapter 9).

Secondary hypothyroidism is caused by failure of the hypothalamic – pituitary – thyroid hormonal axis leading to deficient secretion of hormones by the hypothalamus or pituitary, caused by:

• known damage to the hypothalamus or pituitary as a result of previous surgery, meningitis, trauma or radiation to the brain

• the development of tumours or cysts.

The Healthy Thyroid: What you can do to prevent and alleviate thyroid imbalance

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