Читать книгу Algorithms in Bioinformatics - Paul A. Gagniuc - Страница 21

The stochastic behavior of brownian motion (random walk) and the concentration gradients, scatter the mRNA molecules from the origin of synthesis to other locations with a lower concentration. Thus, the mRNA scattering (as is the case with many other molecules of different sizes and shapes) is done naturally on the least frictional paths. In the case of eukaryotes, the origin of pre-mRNA synthesis and processing is the inner space of the cell nucleus (high mRNA concentration) and the mRNA molecules diffuse through the nuclear pores into the relaxed environment of the cytoplasm (low mRNA concentration). In the case of prokaryotes, the mRNAs diffuse from the origin of synthesis (which is close to the DNA molecule floating directly in the cytoplasm) into the rest of the cytoplasm. The information from some mRNAs allows for protein synthesis, whereas the information from other RNAs provides direct biological functionality. Moreover, some mRNA molecules become functional by themselves due to a self-complementary between different regions of the same molecule. Other RNA molecules become functional after they are processed by different proteins (or vice versa).