Читать книгу Shear's Cysts of the Oral and Maxillofacial Regions - Paul M. Speight - Страница 36

The age distribution of 948 patients in South Africa is shown in Figure 3.1. Very few cases are seen in the first decade, after which there is a fairly steep rise, with a peak frequency in the third decade and large numbers of cases in the fourth and fifth decades. In a Sheffield study of 1970 cases, Jones et al. (2006 ) found cysts in older age groups, with a peak in the fourth decade and a mean age of 37.3 years (Figure 3.2). Similar data were found in French (Meningaud et al. 2006 ), Australian (Johnson et al. 2013 ), Italian (Lo Muzio et al. 2017 ), and Greek (Tamiolakis et al. 2019 ) studies, with mean ages of 40.8, 50.5, 38.2, and 41.2 years, respectively. The older ages of these patients compared with the South African patients was noted in previous editions of this book and suggests that the South African patients may have been exposed to the relevant aetiological factor, mainly dental caries, at a slightly younger age than the other groups.

The wide age range of lesions, the very low frequency in the first decade, and a peak in the fourth decade have been confirmed in a number of studies (Tortorici et al. 2008; Sharifian and Khalili 2011 ; Ramachandra et al. 2011 ; Soluk Tekkeşin et al. 2012b ; Lo Muzio et al. 2017 ; Tamiolakis et al. 2019 ). These studies also indicate that although dental caries is very common in children, radicular cysts are not often associated with deciduous teeth. Soluk Tekkeşin et al. (2016 ) identified 596 odontogenic cysts in a paediatric population (age 0–17 years), of which 387 (65%) were radicular cysts (including 17 residual cysts). Of these, only 3 arose in subjects less than 6 years old, 113 were found in the mixed dentition (age 6–12 years), and 271 were associated with permanent teeth (age 13–17 years). In a similar study in Brazil, da Silva et al. (2018) reviewed 294 odontogenic cysts in subjects younger than 20 years. They identified 145 radicular cysts, but only 9 arose in subjects younger than 10 years.

Figure 3.1 Age distribution of 948 South African patients with radicular cysts.

Figure 3.2 Age distribution of 1970 patients with radicular cysts from Sheffield, England, 1990–2004 (n = 1970).

Source: Based on Jones et al. (2006 ).

Residual cysts are very unusual in the first, second, or third decades and peak at a slightly older age, usually in the fifth decade. Lo Muzio et al. (2017 ) found a mean age of 49.4 years (n = 218; range: 17–90) and, in their large Greek series, Tamiolakis et al. (2019 ) found a mean age of 50.5 years (n = 749; range 11–93) for residual cysts.