Читать книгу Essentials of Nuclear Medicine Physics, Instrumentation, and Radiation Biology - Rachel A. Powsner - Страница 72

1 Which of the following statements are true about medical radionuclide generators:The parent nuclide always has a shorter half‐life than the daughter nuclide.If the T1/2 of the parent nuclide is 50 times greater than the T1/2 of the daughter nuclide the equilibrium portion of the activity curve is basically flat and is categorized as “secular” equilibrium.The parent nuclide is less tightly bound to the column than the daughter nuclide.All of the above.None of the above.

2 True or False: During an equilibrium state within a 99Mo–99mTc generator the total activity of 99mTc is always less than the total activity of 99Mo because 14% of 99Mo decays directly to 99Tc, bypassing the metastable state.

3 Which of the following is an example of a generator that reaches secular equilibrium?99Mo–99mTc.82Sr–82Rb.

4 Associate each of the following terms (a) through (k) with the most appropriate of the three methods of nuclide production listed here (a term can apply to more than one method):Reactor.Cyclotron.Generator.Moderator.Chain reaction.Thermal neutron.Dee.Control rod.Target.Cow.Pig.Column.Elution.By‐product.

5 Associate each of the following nuclear reactions (a) through (d) with the most appropriate of the three listed production methods.Cyclotron.Fission reaction (reactor).Neutron capture (reactor).111Cd(p,n)111In.68Zn(p,2n)67Ga.235U(n,f)99Mo.98Mo (n,γ)99Mo.

6 18F is produced:In a generator.In a cyclotron.From by‐product material of nuclear fission.By neutron bombardment in a nuclear reactor.

7 99Mo is produced (select all that apply):In a generator.In a cyclotron.From by‐product material of nuclear fission.By neutron bombardment in a nuclear reactor.

8 99mTc is produced:In a generator.In a cyclotron.From by‐product material of nuclear fission.By neutron bombardment in a nuclear reactor.

9 The half‐life of 99mTc is 6 hours and the half‐life of 99Mo is 66 hours. At 8 AM Monday morning, the Tc/Mo generator is eluted of all 99mTc and the yield is 86 mCi. Approximately how much total 99mTc will we be able to elute from the generator on Friday at 8 AM.Essentially zero since more than 10 half‐lives have elapsed.31 mCi.86 mCi.54 mCi.