Читать книгу Principles of Virology, Volume 2 - Jane Flint, S. Jane Flint - Страница 110

1 Which of the following can impact the ability of a barrier to prevent infection of an individual host? (Select all that are appropriate.)Time of year and humidityGenetics of the potential hostConcentration of the viral inoculumHealth of the host

2 Not all virus encounters with receptor-bearing cells lead to a productive infection. List four obstacles that could preclude a productive infection.

3 What host and viral parameters govern whether a virus will remain localized or can disseminate into other tissues?

4 Define three ways by which viruses can gain access to the brain, and provide an example for each.

5 For each of the following potential portals of entry, define key anatomical and/or physiological barriers that might prevent infection. (Select all that are appropriate.)Portals of EntrySting from an infected arthropodInhalation of virus-laden aerosol dropletsIngestion of virus-contaminated foodsExposure to semen from an infected maleKeratinized dead cell layerMucusLow pHBlood-brain barrier