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1.6.3 Aetiology/Risk Factors

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 Caused by mutations or altered expression in five genes:AMEL (amelogenin)ENAM (enamelin)MMP20 (matrix metalloproteinase‐20)KLK4 (kallikrein‐4)FAM83H. 6–16

 Inheritance can be autosomal dominant, recessive or x‐linked

Handbook of Oral Pathology and Oral Medicine

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