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When the first edition of this book, Poison Arrows, was published in 2005 it was warmly welcomed by the scientific press and those with an interest in medicine and physiology. It was the subject of BBC science programmes. The publisher, John Blake, insisted the story was too interesting and too important not to be accessible to a much wider audience of lay readers. And he persuaded me to write From Poison Arrows to Prozac.

In writing this book I would like to acknowledge the contribution of Stuart Robertson, of John Blake Publishing, whose suggestions and criticism have helped shape it; the assistance of my ever-critical proofreader, my wife Carole, and the patience of my friends, who have provided information, and my colleagues at Chelsea and Westminster Hospital, who served as guinea pigs for many of the experiments described in the book.