Читать книгу Cell Biology - Stephen R. Bolsover - Страница 95
Medical Relevance 4.1 Inhibiting DNA Polymerase Fights Cancer
ОглавлениеDrugs that inhibit DNA replication prevent cells dividing. Cytarabine (also known as cytosine arabinoside and arabinofuranosyl cytidine) is sold as Cytosar‐U, Tarabine PFS, Depocyt, and AraC. It inhibits eukaryote DNA polymerases α, δ, and ε, and is therefore widely used to treat cancers. It is on the World Health Organization's model list of essential medicines.