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CHAPTER III.
SECONDARY INFECTION IN THE WARD TREATMENT OF INFLUENZA AND PNEUMONIA

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Eugene L. Opie, M.D.; Francis G. Blake, M.D.; James C. Small, M.D.; and Thomas M. Rivers, M.D.

One of the most pressing problems that presented itself in the care of influenza and pneumonia patients in the army cantonments during the recent epidemic was the danger of secondary contact infection because of the overcrowding of the base hospitals, nearly all of which were taxed far beyond the limits of their capacity. That this danger was very real was fully demonstrated by certain studies in ward infection that this commission was able to make at Camp Pike49. It is the purpose of the present section of the report to present these studies and to discuss the means whereby this danger may be most successfully met.

It is perhaps well, first to define exactly what is meant by secondary contact infection in influenza and pneumonia. In our experience at Camp Pike it was found that a very large percentage of the pneumonias following influenza were accompanied by secondary infection with pneumococcus, some few being caused by hemolytic streptococcus. The types of pneumococcus encountered were almost entirely those that are found normally in the mouths of healthy men, approximately 85 per cent being Types II atypical, III, and IV. It has been generally accepted that infection with these types of pneumococci is usually autogenous—that is, that under the proper conditions of lowered resistance an individual becomes infected with the pneumococcus that he carries in his own mouth. Many observations made during the course of the present work have suggested that this is probably not so in many instances and that the influenza patient may not be so much in danger from the pneumococcus that he normally carries in his own mouth as he is from that carried by his neighbor, in other words, he is in danger from contact infection. The same considerations hold true with respect to hemolytic streptococcus infection. Secondary contact infection in cases of already existing pneumonia following influenza were found to occur frequently. These were for the most part caused by hemolytic streptococcus infection superimposed upon a pneumococcus pneumonia. Many instances of double pneumococcus infection, however, either coincident with or following one another were encountered.

Epidemic Respiratory Disease

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