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Protein Secretion and Export

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Some proteins are transported through the membrane(s) to the outside of the cell, where they can remain attached, enter the surrounding medium, or even directly enter another cell. The process differs markedly between cells that have or lack an outer membrane. Bacteria that have an outer membrane require translocation from the periplasm through the extremely hydrophobic outer membrane. Because of the additional challenge created by the outer membrane, these bacteria have developed elaborate specialized structures to export proteins. Many of these play important roles in bacterial pathogenesis, so they have attracted considerable attention.

Snyder and Champness Molecular Genetics of Bacteria

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