Читать книгу Cobert's Manual Of Drug Safety And Pharmacovigilance (Third Edition) - William Gregory - Страница 78

The “grand daddy” of drug safety “regulatory agencies” dates back to 18th century Japan, when the eighth shogun, Yoshimune Tokugawa (1716–1745), upon recovering from an illness, awarded 124 medicinal traders in Osaka special privileges to examine medicines throughout the country. However, the safety of the medicines was difficult to guarantee despite these efforts. A shrine in Osaka, called Shinno-san, was created and dedicated to Shinno, the guardian of the pharmaceutical industry and the divine founder of medicine from China. This information was found at the Osaka tourism website.