Отрывок из книги
The text delves into topics related to the evolution of forms of matter movement: physical, chemical, biological, and conscious. It introduces the concepts of the Pan-socium, Pan-encephalon, and Superintelligence. The author reflects on the formula of matter evolution, defines life, explores multicellularity and intelligence, and hypothesizes that love is a crucial organizing force of the mind. The interrelation of music and human consciousness, as well as the connection between mental disorders and consciousness, is examined. The author characterizes emotional activity as a specific reactivity inherent in the mind and thought as an organizing force regulating emotional activity. Schizophrenia is discussed as a disease of meaning reproduction, and parallels are drawn between cancer, as a disease of mitosis, and schizophrenia. The evolution from physical forms to intelligent ones is explored, along with metaverses, linguistic models, blockchain, and biotechnologies in the context of the Pan-socium and Pan-encephalon. The text contemplates the cosmic role of humans and superintelligence.
At that time, I was deeply fascinated by chemistry and biology. I viewed life as a continuation of chemistry. In physics, I was particularly drawn to the field of thermodynamics. Beyond the school curriculum, I remember reading Peter Atkins’ popular book «Order and disorder in nature» [16]. I was familiar with the concept of entropy and aware of the anti-entropic properties of life. I also studied Academician A. I. Oparin’s book on the origin of life from coacervate droplets [8]. Magazines such as «Science and life», «Technology for youth», and «Chemistry and life» were invaluable resources for me, as they often discussed the topic of the origin of life. My go-to book was «The Universe. Life. Mind» by I. S. Shklovsky, which devoted significant attention to life, intelligence, and their cosmic role [14]. I didn’t overlook the works of V. I. Vernadsky, reading some of his writings as well [3]. I was also captivated by Erwin Schrödinger’s book «What is Life? From a Physicist’s Viewpoint» [15]. Thus, my father’s idea that “life is a hierarchy of enzymatic systems” found fertile ground in my prepared mind.
.....
Much later, together with Professor A.M. Seledtsov, I co-authored an article for a student collection titled "Calcium Ions, cerebral paroxysms, epileptogenesis, mitosis, and apoptosis"[13]. At the time, we hypothesized that the calcium-calmodulin complex and nitric oxide are among the most ancient intracellular messengers. One of the most critical functions of calcium ion regulation in the nervous system is its role in apoptosis. Some effects of calcium ions on nervous tissue are temporally organized in a paroxysmal manner, primarily concerning pathological phenomena (epileptic paroxysms, the activation of pathological cravings for alcohol). Despite existing cellular calcium defenses, vertebrates – with their calcium-based skeletons – are prone to numerous pathological processes where hypercalcicity (an elevated concentration of calcium ions within the cell) plays a key role. These processes are temporally organized either paroxysmally (e.g., epileptic seizures, activation of alcohol cravings, certain cardiac arrhythmias) or non-paroxysmally (e.g., affective disorders, arterial hypertension).
We hypothesized that paroxysms in cases of hypercalcicity represent a process by which a cell (neuron) eliminates excitotoxicity, which would otherwise lead to apoptosis. This is most clearly observed in motor epileptic seizures. In such cases, the chemical energy of excitotoxicity is transformed into mechanical energy. The ease of this transformation is explained by the shared ontogenetic and phylogenetic origins of the nervous and locomotor systems. Specifically, in neurons, the calcium-calmodulin complex acts as a transformer of chemical energy into electrical energy, while in skeletal muscles, the calcium-troponin complex converts electrical energy into mechanical energy. In both cases, calcium ions and structurally similar proteins – calmodulin and troponin play a leading role in energy transformation. Sometimes, the epileptic mechanism only partially prevents apoptosis, and some neurons die. Clinically, this can manifest as Todd’s paralysis, a well-known phenomenon.
.....
