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Medication overdose

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Intentional insulin overdose has been reported with some frequency in the literature. Persistent or refractory hypoglycemia should prompt the EMS clinician to consider the possibility of overdose, whether intentional or unintentional. Treatment should be aimed at restoring glucose levels to a normal range, continued monitoring of glucose levels, and transport to an ED for continued monitoring and care. Unrecognized profound hypoglycemia carries a significant risk of hypoglycemic encephalopathy, causing lifelong cerebral dysfunction [41]. Recurrent hypoglycemia has been reported for 2‐3 days in patients with massive overdoses [42–44].

Emergency Medical Services

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