Читать книгу Anti-Aging Therapeutics Volume XVI - A4M American Academy - Страница 37

We have determined a number of important significant correlations with multiple hormone alterations associated with menopause. Most interestingly, menopausal patients suffer from both somatic and neurological deficits, which we have now found to be significantly associated with certain hormonal correlates, specifically pregnenolone with a somatic cluster and TSH with a neurological and musculoskeletal cluster, which agrees with the current literature.

Moreover, menopausal symptoms and symptoms in medicine in general are multifactorial, depending on each person’s biological and genetic makeup. It is not surprising that one set hormonal pattern is unable to predict any particular cluster of menopausal symptoms. Instead, multiple hormones have been related to numerous clusters of menopausal symptoms in patients that have multiple endocrine abnormalities. This study highlights the need to test the core biological endocrine hormones associated with menopause, and to establish a standard in evaluating menopause from a multi-hormonal perspective. We propose a new paradigm shift whereby we replace the old nomenclature of HRT to MHRT.