Читать книгу Type 2 Diabetes in Children and Adolescents - Arlan L. Rosenbloom - Страница 13
Insidious Onset
ОглавлениеObese individuals who are not African American or who are African American but do not have a three-generation history of early-onset diabetes in a dominant pattern can be considered to have type 2 diabetes.
Islet autoantibody testing will be helpful in a lean patient. The presence of antibodies indicates type 1 diabetes picked up early; the absence of antibodies may indicate MODY.
Because MODY is rare, routine testing for the various mutations that have been described is not of value.
Fasting C-peptide or insulin measurements, if insulin treatment has not been given, may be of value after stabilization; elevated levels are indicative of type 2 diabetes. Repeat testing at 1 year or later may be needed for individuals with normal results.