Читать книгу Type 2 Diabetes in Children and Adolescents - Arlan L. Rosenbloom - Страница 7
C H A P T E R 2 Diagnosis and
Classification of
Diabetes in Children DEFINITION
ОглавлениеThe diagnosis of diabetes includes a wide array of diseases that are characterized by persistent hyperglycemia (Table 1).
Insulin is the only physiologically significant hypoglycemic hormone. Therefore, hyperglycemia must be the result of impaired secretion of insulin from the β-cells of the pancreas; resistance to the effect of insulin in the liver, muscle, and fat cells; or a combination of these pathophysiologic situations.
The current criteria for diabetes include categories of impaired glucose tolerance (IGT) and impaired fasting glucose that are considered to be states of pre-diabetes, reflecting an appreciation of the fact that these preclinical states are associated with increased cardiovascular morbidity (1).
