Читать книгу Anti-Inflammatory Diet For Dummies - Artemis Morris - Страница 50
IS METABOLIC SYNDROME A CAUSE OR EFFECT OF INFLAMMATION?
ОглавлениеMetabolic syndrome occurs when a person has a series of metabolic symptoms that, when combined, put the person at an increased risk of coronary heart disease, stroke, and type 2 diabetes. The American Heart Association lists these symptoms as the core group resulting in metabolic syndrome:
Abdominal obesity (excessive belly fat)
Elevated triglycerides (blood fat disorders that create plaque buildup)
High blood pressure
Insulin resistance/glucose intolerance
Increased risk and susceptibility to blood clotting
Inflammatory state (elevated C-reactive protein in the blood)
In metabolic syndrome, the enemy is excessive insulin caused by insulin resistance, which creates an imbalance between blood sugar (glucose) and insulin. The cells of the body become resistant to the insulin’s attempts to bring the glucose into the cells, and the pancreas produces more insulin to try to make up for this.
Insulin resistance is worsened by inflammatory signals because inflammation does not allow the cells of the body to take in glucose; therefore, sugar levels rise in the blood and can get high enough to cause diabetes. Inflammation kicks in to battle the insulin resistance, creating elevated hs-CRP levels and other cytokines, and increasing the risks of stroke and coronary heart disease.
Cortisol is your body’s natural anti-inflammatory chemical and is produced in high amounts during chronic stress and obesity. Cortisol helps keep energy on track by determining the right type and amount of carbohydrate, fat, or protein that your body needs at any particular time. It moves the body’s fat stores from one location to another and prevents the release of substances in the body that lead to inflammation.
Cortisol’s response to inflammation is to produce more fat cells around the abdomen (belly fat), which then increases fluid retention, raises blood pressure, increases blood sugar and the risk of insulin resistance, and increases the risks of memory loss and muscle and bone weakness.