Читать книгу Synopsis of Orthopaedic Trauma Management - Brian H. Mullis - Страница 17

A. Physiology of fracture healing is an orchestrated set of events from the organ system level to the cellular level, down to and including complex intracellular processes.

B. Multiple organ systems are involved including bone, endocrine, vascular, gastrointestinal (e.g., overall nutrition and vitamin D), kidneys, immune, and respiratory systems.

C. At the local bone level there are two types of fracture healing, primary/intramembranous and secondary/endochondral.

D. Formation of new bone at a fracture site is the ultimate macroscopic outcome of cellular and intracellular events.

E. The goal of fracture surgery is to create a mechanical environment that optimizes the biology of fracture physiology to promote bony union.