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Two major pathways deliver sensory information to the thalamus and thence to the cortex (Figure 2.8):

 Spinothalamic pathways (nociceptive – pain, temperature);

 Posterior columns → medial lemnisci (touch, position, movement, vibration).

Each system consists of three orders of neurones.

 First order neurones are in the posterior root (dorsal root) ganglia;

 Second order neurones decussate before reaching the thalamus;

 Third order neurones project from thalamus to cortex;

There is somatotopic organisation throughout, and transmission can be controlled (inhibited/enhanced) at various stages (see Gate Control & Chapter 23).