Читать книгу Structure and Function of the Bacterial Genome - Charles J. Dorman - Страница 34

The MaoP protein is important for the organisation of the Ori macrodomain (Duigou and Boccard 2017; Valens et al. 2016). It binds to a 17‐bp sequence that lies adjacent to the maoP gene. Both MaoP and maoS are required for accurate positioning of Ori within the cell during the division cycle and for restricting the ability of the Ori macrodomain to interact with other territories of the chromosome, especially the Right Macrodomain and the NS‐Right region (Valens et al. 2016). MaoP has been described as belonging to a class of DNA‐binding proteins that has co‐evolved with Dam, including MatP (see below), MukBEF, and SeqA: all of these proteins are involved in chromosome replication/segregation (Brezellec et al. 2006; Valens et al. 2016).