Читать книгу Neurobiology For Dummies - Frank Amthor - Страница 107

Making Spikes with Sodium and Potassium Channels

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Imagine a neuron at its resting potential of about –65 mV. Some other neuron that is presynaptic to this one releases glutamate, which binds to the first neuron’s excitatory glutamate receptors. This process opens a glutamate receptor, which passes a (mostly) sodium current. Sodium rushes into the cytoplasm from outside the neuron and depolarizes it, reducing potential across the membrane from –65 mV to around –20 mV. This is above the threshold for voltage-gated sodium channels in the first neuron’s membrane, which are now open.

Neurobiology For Dummies

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