Читать книгу Clinical Pharmacology and Therapeutics - Группа авторов - Страница 118

Research was traditionally divided into basic and applied clinical research studies, with basic research involving in‐vitro or animal studies and clinical research involving patients. This model was limited by a lack of integration that contributed to delays in applying basic research into meaningful treatments for patients. More recently, the research community has moved towards an integrated and translational approach where studies involve basic and clinical components, or where basic research is more closely tailored to clinical need with results used to quickly and appropriately guide the development of clinical research. We are now seeing further evolution of the research focus towards precision or stratified medicine. This involves identifying treatments that are most likely to be effective for individual patients or groups based upon bioinformatic and pharmacogenomic data aiming to increase the efficacy, safety and cost‐effectiveness of new treatments.