Читать книгу Clinical Pharmacology and Therapeutics - Группа авторов - Страница 43

Mr A.R., a 78‐year‐old man weighing 72 kg and with a creatinine clearance of 24 mL/min, has been taking 250 μg digoxin daily to control atrial fibrillation. He presents to his general practitioner with anorexia and nausea a month after starting therapy. A digoxin concentration of 3.6 µg/L (4.6 nmol/L) is measured.