Читать книгу Gastrointestinal Surgical Techniques in Small Animals - Группа авторов - Страница 23

A septic peritonitis interferes with healing of an intestinal anastomosis because it reduces collagen content at the level of the anastomosis. The combination of bacterial and neutrophil collagenases increases the collagen fibers breakdown. The collagen synthesis and deposition are reduced by the peritonitis (Ahrendt et al. 1996; Munireddy et al. 2010). The septic exudate present in the anastomosis prevents synthesis and deposition of collagen and angiogenesis (Thornton and Barbul 1997).