Читать книгу Gastrointestinal Surgical Techniques in Small Animals - Группа авторов - Страница 30

Suture materials are manufactured from natural and synthetic sources. Natural absorbable sutures mentioned in this chapter include catgut and chromic catgut. Absorption of catgut is unpredictable because it is degraded by proteolytic enzymes and phagocytosis and causes a marked tissue inflammatory response that may be detrimental to healing. Pre‐existing tissue inflammation and enzymatic digestion from gastric enzymes can lead to rapid catgut suture degradation. These aforementioned suture characteristics have nearly made natural sutures made of catgut obsolete in small animal surgery.

Synthetic absorbable monofilament suture materials are preferred for gastrointestinal surgery. Synthetic sutures are degraded by controlled hydrolysis making their absorption from tissue highly predictable. The degradation of most synthetic sutures is accelerated in alkaline environments, except for polydioxanone. This suture degrades rapidly in highly acidic environments, so, theoretically, other synthetic absorbable sutures may be better choices when exposed to gastric contents (Freudenberg et al. 2004). The stomach generally heals quickly, so more rapid absorption of polydioxanone from the wall may not be clinically important.