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 Cannot differentiate between benign and malignant liver masses.

 Cannot be the sole diagnostic indicator used in the diagnosis of biliary obstruction.

 Cannot diagnose liver conditions based on echogenicity.

 Cannot reliably determine liver size, or hepatomegaly versus microhepatica.

 Cannot rule out severe liver disease such as hepatic neoplasia and cirrhosis or infiltrative processes based on an unremarkable focused liver examination.