Читать книгу The SAGE Encyclopedia of Stem Cell Research - Группа авторов - Страница 181

Acromegaly is a syndrome in which there is an abnormality in the anterior pituitary gland, causing the release of large quantities of growth hormone. This results in abnormal growth of bone, especially in the mandible and the anterior portion of the skull. The overgrowth of the mandible results in malocclusion of the jaw, abnormal spacing of the teeth, and prognathism of the jaw. Due to the abnormal osteogenesis, the bone that is produced is of abnormal composition and structure. This can lead to arthritis.