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Definition

Suture‐related tissue reaction is a local inflammatory response induced by the suture material.

Risk factors

 Suture material

 Inappropriately large suture

 Excessive suture material

 Inappropriate suture technique

 Excessive tension

Pathogenesis

Tissues react to all suture material regardless of the type of suture material used [9]. Excessive tissue reaction to suture results in edema, tissue friability, and subsequent suture failure [9]. Usually, the inflammatory reaction is most prominent at the knot site, since the knot represents the major foreign body mass and density, and causes the most mechanical trauma to the tissues [22].