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Tissue Processing in the Endoscopy Laboratory

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An excellent recent review on the topic of tissue acquisition has been published by the American Society for gastrointestinal endoscopy. For most routine tissue sampling the biopsy material is placed in formalin and subsequently embedded in paraffin for histological analysis. Other specific preparations include sampling for microbiological evaluation, molecular or genetic testing, and electromicroscopy. These special samples should be handled according to local institutional guidelines. In general, samples that are obtained for culture should be obtained prior to placing forceps into formalin as formalin residue can destroy or inactivate live microbial tissue.


Figure 1.9 (a) and (b) Endoscopic ultrasound endoscope and guided fine‐needle aspiration (EUS‐FNA) device.

Gastrointestinal Pathology

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