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H. pylori Sampling

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Biopsy is one of several recommended methods for H. pylori sampling that also includes urease breath testing and stool testing for H. pylori antigen. When using endoscopic tissue sampling, there are two general methods including non‐histological testing of the tissue for the presence of urease using the traditional Campylobacter‐like organism test (CLO‐test). In this case, the tissue should be placed in the standard agar well and visually inspected for a pH change following the instructions for use in this product. Histological sampling can also be performed with one of two methods. One method is to take three biopsies including one from the angularis corpus antrum junction, one from the greater curvature of the corpus, and one from the greater curvature of the antrum. Alternatively, the updated Sydney protocol may be followed, which includes five biopsies including one from the antrum lesser curve, antrum greater curve, gastric corpus lesser curve, and greater curve, and one from the angularis of the stomach.

Gastrointestinal Pathology

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