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Diagnostic Sampling

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Currently established protocols for sampling for celiac disease recommend four to six biopsies from the duodenum including the duodenal bulb and distal duodenum.

All other suspicious areas should be sampled using routine biopsy technique. Sampling of the papilla should be performed with caution as biopsy in this area can cause pancreatitis. When a suspected neoplastic lesion is seen in the region of the papilla, it is preferred to take a biopsy that does not immediately injure the orifice of the bile duct or the pancreas duct.

Gastrointestinal Pathology

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