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Disorders of Fluid and Electrolyte Metabolism
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Frontiers of Hormone Research
Disorders of Fluid and Electrolyte Metabolism
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Contents
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Historical Aspects of Hyponatremia
Early Publications and Theories
Early Descriptions of SIAD
Measurement of Plasma Vasopressin Levels
Development of Animal Models of Hyponatremia
Recent Advances
References
Страница 15
Physiology and Pathophysiology of Water Homeostasis
Abstract
Physiology of Water Homeostasis Introduction
Plasma Tonicity
Determinants of Plasma Tonicity
Determinants of Plasma Sodium Concentration
Water Balance
Tonicity Sensing Mechanisms
Thirst
Vasopressin
Renal Handling of Water
Loop of Henle
Distal Tubule and CDs
Mechanisms of Urinary Concentration
Homeostatic Response to Changes in Plasma Tonicity
Pathophysiology of Disorders of Water Homeostasis: Hyponatremia
Increased Free Water Intake
Decreased Renal Free Water Excretion
Decreased Glomerular Filtration
Decreased Solute Intake
Increased Vasopressin Activity
Decreased EABV
Syndrome of Inappropriate ADH Secretion
Cortisol Deficiency
Thiazide-Induced Hyponatremia
References
Страница 42
Etiology and Epidemiology of Hyponatremia
Abstract
Etiology of Hyponatremia
Epidemiology of Hyponatremia
Hyponatremia in Geriatric Patients
Hyponatremia in the Emergency Department
Hyponatremia in the Postoperative Setting
Hyponatremia in the Intensive Care Setting
Conclusion
References
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