Читать книгу Unveiling Diabetes - Historical Milestones in Diabetology - Группа авторов - Страница 50

Frederick Madison Allen (1879–1964) graduated from the University of California at Berkeley and completed his M.D. there in 1907. He spent the years 1909–1912 as a teaching fellow at Harvard Medical School, conducting experiments on cats and dogs, largely at his own expense. An austere man, he describes himself in an unpublished memoir (private collection of Alfred Henderson, Bethesda, MD, USA) as living like a hermit, continually working 7 days a week.

Allen produced diabetes in his animals by partial pancreatectomy, the degree of disease depending on how much pancreas was removed. According to his friend and biographer Alfred Henderson, “There resulted from this experimental period a mass of manuscript material, all written in longhand which appeared capable of considerable improvement. No publisher could be found to wade through his crude manuscript” [7]. With a subsidy from Allen’s father, Harvard University Press published the manuscript as Studies Concerning Glycosuria and Diabetes, which ran to 1,179 pages. In this book, Allen gives no prescription for calorie deprivation as a therapy for human diabetes, nor does he describe any felicitous effect of starvation on his animal subjects. To the contrary, Allen occasionally reaches conclusions that seem counter to his later position, for example, “Fat feeding is not to be feared in diabetics” [8].