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This eighth edition marks the 42nd year of this text and reflects the continuing remarkable advances made in achieving accurate prenatal and preimplantation diagnoses. The first book on this subject (The Prenatal Diagnosis of Hereditary Disease) was published some 48 years ago (by AM). The distillation of accrued biological, technological, ethical, and legal knowledge has graced these pages and enriched the reference value of these editions. The wisdom, insight, perspective, expertise, experience, and knowledge of these senior contributing authors has made these volumes a valuable and authoritative text. Moreover, these authors have again provided an international perspective, this edition having contributions from nine countries.

Expert care in human genetics, maternal–fetal medicine, and perinatal medicine has demanded knowledge, up‐to‐date information, guidance, and expertise in each volume. This has been achieved only by the willingness of the internationally recognized authoritative authors who have taken the time to share their knowledge, experience, and wisdom. For this we are most appreciative.

We are also grateful and indebted to our friends and colleagues who have died and who were expert contributing authors to earlier editions. We remember them with pride and sadness: Bruno Brambati, MD, David J.H. Brock, PhD, Jacob A. Canick, PhD, Louis Dalliaire, MD, PhD, Sherman Elias, MD, H.J. Evans, PhD, FRSE, John C. Fletcher, PhD, Fredric Frigoletto, MD, Albert B. Gerbie, MD, Leonard A. Herzenberg, PhD, George Hug, MD, Lillian Y.F. Hsu, MD, Mary Z. Pelias, PhD, JD, Arthur Robinson, MD, Richard H. Schwarz, MD, Margery W. Shaw, MD, JD, Irving Umansky, MD, Yury Verlinsky, PhD, and Dorothy C. Wertz, PhD.

It is possible that we are unaware of the passing of a few authors and regret any omission. We remain eternally grateful to all these remarkable physicians and scientists.

AM deeply appreciates the exemplary work and dedication to perfection of his assistant Marina Nguyen. JM is very grateful for the precision, accuracy, and patience of his assistant Emma Rebholz during the writing and editing of this text.

Aubrey Milunsky

Jeff M. Milunsky