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The inability to sire offspring is referred to as impotence and may result from abnormalities in sperm production and/or inability to copulate. Inability to copulate (impotentia coeundi) is further divided into inability to perform the copulatory act due to physical limitations and inability to copulate due to erection failure (impotentia erigendi). This chapter reviews important causes of impotence due to abnormalities of the genitalia of the bull. Abnormal spermatogenesis is covered in Chapters 3 and 5.