Читать книгу Selenium Contamination in Water - Группа авторов - Страница 62

To date, only experimental selenosis in camels has been reported. One study by McDonald et al. (2011) reported that Se doses with 1 and 2 mg/kg body weight caused lassitude, inappetence, inability to raise, mild pulmonary congestion, alveolar edema, acute myositis, and edema in a different portion of the brain. Administration of 0.051–0.095 mg Se/kg LW to camels caused selenosis (Seboussi et al. 2008). Faye and Seboussi et al. (2008) reported that 8 and 12 mg Se/day administration caused several clinical symptoms such as hair discoloration, followed by alopecia, dark watery diarrhea, inferior cervical lymph increase, dyspneic respiration, and difficulty in walking. Pathological alterations in kidney, heart, and liver were also observed, such as congestions in Bowman's space and convoluted tubules, the proliferation of Purkinje fibers, degenerative changes in myofibers, degenerative changes hepatic cells of the hepatic lobules, edema in intercostal and diaphragm muscles, perivascular edema in brain, etc. (Figure 4.3a–l). Aitken (2001) reported that selenosis showed mainly hoof lesions in horses, along with decreased body growth.