Читать книгу Biomedical Data Mining for Information Retrieval - Группа авторов - Страница 33

Gene expression analysis consists of transcription and translation of a particular gene from its coding region. If there is any change in coding sequence automatically gene product’s structure and function change. A variety of techniques are there which analyze gene expression qualitatively and quantitatively. If there are some gene sequence changes automatically the biological functions of gene products would change. To get a better understanding of gene, gene pathways, gene associated signaling pathways, biological functions of gene, analysis of gene expression has to be done which are very useful in research, pharmaceutical and clinical fields. Gene expression analysis covers the static information of the genome sequence into a dynamic functional view of an organism’s biology. There are various approaches like Real-time PCR, Serial analysis of gene expression (SAGE), Microarrays, next generation sequencing (NGS) are used for study and analyze the gene expression patterns. These techniques are proven to be a very effective tool for Gene expression analysis.