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Preface

The past couple of years will be remembered for the COVID-19 pandemic and ensuing lockdowns, wherein almost every country saw a series of lockdowns and consequent suffering. To overcome the pandemic, the discovery of vaccines and other alternative therapies were attempted worldwide. Currently, the discovery of new solutions to the pandemic can be facilitated through the use of promising bioinformatics techniques and integrated approaches. Hence, this book provides readers with an understanding of the use of bioinformatics tools in new drug design and the discoveries which are inevitable in the present situation. The book covers a broad spectrum of the bioinformatics field, starting with the basic principles, concepts, and application areas under multidisciplinary sections. Also covered is the role of bioinformatics in drug design and discovery, including aspects of molecular modeling. Some of the chapters provide detailed information on bioinformatics-related topics, such as silico design, protein modeling, DNA microarray analysis, DNA-RNA barcoding, and gene sequencing, all of which are currently needed in the industry. Also included are specialized topics, such as bioinformatics in cancer detection, genomics and proteomics, which are highly relevant to the present scenario. Moreover, a few chapters explain highly advanced topics, like machine learning and covalent approaches to drug design and discovery, all of which are significant in pharma and biotech research and development. Therefore, the contents of this book will be useful for students, scientists, researchers, and professionals working in the field of bioinformatics, drug design, pharmacoinformatics and medicinal chemistry under the umbrella of academia and industry.

Our sincere gratitude especially goes to all the contributors for their useful insights concerning bioinformatics and its multidisciplinary applications. We sincerely thank Scrivener Publishing for their assistance, constant support, and patience in finalizing this book.

S. Balamurugan Coimbatore, India

Krishnan Anand Bloemfontein, South Africa

Dinesh Goyal Jaipur, India

Balakumar Chandrasekaran Amman, Jordan

Boomi Pandi Karaikudi, India

Computation in BioInformatics

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