Читать книгу Computation in BioInformatics - Группа авторов - Страница 12

Rene Barbie Browne, Shiny C. Thomas and Jayanti Datta Roy*

Department of BioSciences, Assam Don Bosco University, Sonapur, Assam, India

Abstract

Drug discovery is the method of identifying and validating a disease target and discovering and developing a chemical compound which can interact with its specific target. This process is very complex and time consuming, requiring multidisciplinary expertise and innovative approaches. To overcome the difficulties and complexity, in silico approach is used that reduces the time and expenditure. This chapter addresses the importance of bioinformatics in drug designing. It focuses on bioinformatics tools like AutoDock, LigPlot, FlexX, and many other softwares which play an important role in rational designing of drug. Thus, the main goal of this chapter is to provide an overview of the importance of bioinformatics tools in designing a drug.

Keywords: AutoDock, LigPlot, FleX, GenBank, SWISS-PROT, PDB