Читать книгу Manual of Equine Anesthesia and Analgesia - Группа авторов - Страница 379

 These drugs inhibit acetylcholinesterase, preventing rapid destruction of ACh so that it accumulates at muscarinic and nicotinic receptors.

 Neostigmine and edrophonium are mainly used for reversal of non‐depolarizing neuromuscular blockade (nicotinic effect). Neostigmine has also been administered parenterally to promote GI motility in horses.

 Simultaneous administration of an anticholinergic prevents unwanted muscarinic signs (bradycardia, salivation, bronchospasm, intestinal hypermotility) without preventing the nicotinic effects of ACh.