Читать книгу Biopharmaceutics - Группа авторов - Страница 64

Solute molecules that have a permanent dipole, as a result of the molecular structure, will result in a degree of polarity. Some molecules can be strongly polar whilst others are weakly polar. Van der Waals forces are a result of dipole interactions where compounds with a similar polarity will mix whereas those with differences in polarity will not mix. Attractive forces are the result of the positive head of one molecule positioning itself close to the negative head of another molecule. However, it is also important to consider physical, geometric constraints which may limit the efficiency of mixing.