Читать книгу Fundamentals of Pharmacology for Paramedics - Группа авторов - Страница 37

Medications can come in varying concentrations and formulations for different modes of delivery. Adrenaline is a naturally occurring catecholamine hormone produced by the adrenal glands and is often also administered in the management of life‐threatening presentations such as cardiac arrest, anaphylaxis and croup.

The concentration of adrenaline can be expressed as 1:1000 or 1:10 000. This is expressed verbally as ‘one in one thousand’ and ‘one in ten thousand’ respectively. This ratio refers to the medication mass per volume of solution:

Adrenaline concentrations can and do vary, but the following is a guide to concentrations and routes of administration for various indications:

Concentration	Route of administration	Indication
Adrenaline 1:1000	Intramuscular Nebulised	Anaphylaxis Croup Asthma
Adrenaline 1:10 000	Intravenous	Cardiac arrest Cardiogenic shock