Читать книгу Spiro Compounds - Группа авторов - Страница 26

The versatility and robustness of the different organocatalytic activation modes have been implemented in a number of stereoselective cascade processes, addressing the requests of atom and step economy of modern synthetic chemistry. Remarkably, organocatalysts are generally robust, readily available, and their easy scaffold modifications allow the straightforward generation of different structural variants for the development of highly diversified asymmetric transformations. In this scenario, organocatalytic methodologies represent a powerful strategy for the preparation of complex spiro compounds with high optical purity. The section has been divided into four subsections according to the involved reactions: [3+2] cycloadditions, [4+2] cycloadditions, [4+3]‐, [2+2] cycloadditions and switchable strategies, and miscellaneous reactions.