Читать книгу Pathy's Principles and Practice of Geriatric Medicine - Группа авторов - Страница 368

Galanin is a peptide hormone located in the brain and periphery that stimulates food intake. Available animal evidence does not suggest a decline in galanin levels with ageing, and circulating levels do not differ between young and older women.³⁸ Declining galanin levels are therefore unlikely to contribute to the anorexia of ageing, but reduced sensitivity to galanin might. The effect of ageing on stimulation of feeding by galanin has not been reported in humans, but older women (not men) display a reduced growth hormone secretory response to galanin compared with young adults.³⁹