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Complete blood count

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Usually, the first clinical sign of MDS is the detection of cytopenias (anaemia, leukopenia, or thrombocytopenia) in a complete blood count. For MDS criteria, the cytopenias must be persistent and under specific thresholds (Table 26.1).

Table 26.1 Cytopenia thresholds according to the WHO 2016 Classification.

Hemoglobin <10 g/dL
Platelets <100 × 109/L
Absolute neutrophil count <1.8 × 109/L
Pathy's Principles and Practice of Geriatric Medicine

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