Читать книгу Clinical Obesity in Adults and Children - Группа авторов - Страница 70
Evidence for the heritability of fat mass
ОглавлениеThere is considerable evidence to suggest that, like height, weight is a heritable trait. Genetic epidemiologic studies in different populations can attribute the underlying phenotypic variance of a trait to genetic and/or environmental sources. Longitudinal data from one of the largest family studies, the Quebec Family Study of over 400 families, suggest a significant cross‐trait familial resemblance for parent–offspring (0.20–0.25) and sibling relationships (0.25–0.35) [3]. However, in traditional nuclear families, family members generally share both genes and environment to some degree, so it is difficult to assess the contribution of each component.