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Evidence for the heritability of fat mass

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There is considerable evidence to suggest that, like height, weight is a heritable trait. Genetic epidemiologic studies in different populations can attribute the underlying phenotypic variance of a trait to genetic and/or environmental sources. Longitudinal data from one of the largest family studies, the Quebec Family Study of over 400 families, suggest a significant cross‐trait familial resemblance for parent–offspring (0.20–0.25) and sibling relationships (0.25–0.35) [3]. However, in traditional nuclear families, family members generally share both genes and environment to some degree, so it is difficult to assess the contribution of each component.

Clinical Obesity in Adults and Children

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